Global Dermatology Grand Rounds:
Case of the Month: June 1995
submitted by Dr. Rhett Drugge

September 1996			August 1996
June 1996	May 1996	April 1996	July 1995
June 1995	May 1995	February 1995	January 1995

CASE HISTORY:	PHYSICAL EXAMINATION:
This 79 year old has a several year history of lesions on the penile shaft.	Several small erythematous plaques and plaques with well-demarcated borders were found on the penis.
Click on the images for magnification.
LABORATORY: H&E of the shave biopsy site

His course of treatments have included ketoconazole cream, fluconazole ointment, Tetracycline, Bacitracin ointment, topical 5-fluorouracil 5% cream, and local electrodessication and curettage and have not proven effective.

REFERENCES:
Raiten, K, Paniago-Pereira, C, Ackerman, AB,Pagetoid Bowen's disease vs. extramammary Paget's disease, J Dermatol Surg 1976 Mar; 2(1):24-5
Yamamura, T, Hinda, T, Matsui, Y, Yoshikawa, K, Aozasa, K, Ultrastructural study of extramammary Paget's disease--histologically showing transition from bowenoid pattern to Paget's disease pattern, Br J Dermatology 1993 Feb;128(2):189-93
Powell, FC, Bjornsson, J, Doyle, JA, Cooper, AJ,Genital Paget's disease and urinary tract malignancy, J Am Acad Dermatol 1985 Jul; 13(1):84-90
Hayashi, T, Tsuda, N, Shimada, O, Kishikawa, M, Iseki, M, Nishimura, N, Taniguchi, K, Saito, Y,A clinicopathologic study of tumors and tumor-like lesions of the penis,Acta Pathol Jpn 1990 May; 40(5):343-51
Smith, DJ, Handy, FC, Evans, JW, Falzon, M, Chapple, CR,Paget's disease of the glans penis:an unusual urological malignancy, Eur Urol 1994; 25(4):316-9
deBlois, GG, Patterson, JW, Hunter, SB,Extramammary Paget's disease. Arising in knee region in association with sweat gland carcinoma Arch Pathol Lab Med 1984 Sept; 108(9):713-6
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Global Dermatology Grand Rounds
Rhett J. Drugge, M.D., Founding Editor
50 Glenbrook Road
Stamford, CT 06902 USA
Phone: (203) 324-5719

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